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Polymorphic Isolation


For a drug substance, a certain solid form is often desired for proper dissolution rate (or bioavailability), stability, processability, or intellectual property right. The crystallization process must be capable of selectively producing the desired form with high polymorphic purity and process efficiency.


  • Produce Desired Solid Form
  • We develop processes that isolate the desired solid forms, either anhydrous, hydrate, solvate, amorphous, or co-crystal of APIs.

  • Ensure Polymorphic Purity
  • Our processes are designed and controlled to isolate desired forms selectively and robustly, applying solid understanding of the interplay of involved disciplines as well as available technologies.

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