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Solid Form Screening & Selection


The solid state form of a development candidate compound impacts the development process regardless of the development stage. In order to ensure reproducible exposure from pre-clinical animal trials to clinical studies, some focus on solid state form and formulation is necessary. We provide solutions for development compound form selection and optimization. This includes; candidate form discovery and identification, form evaluation, developability and risk assessment (including processability, stability, etc), and process optimization. We combine our optimized salt/polymorph/co-crystal screening with physicochemical characterization to help clients select the optimal solid form for the development candidate, in addition to describing the associated risks. Our team will develop an optimized process for manufacturing the development candidate focusing on yield, productivity and impurity rejection.


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