Solid state of a drug substance can affect drug properties, API and formulation processing, and drug performance in many ways. For instance, a crystalline salt and a crystalline neutral form of a drug can have drastically different physicochemical properties; two polymorphs of a drug can show very different bioavailability; a solvate and an anhydrate can have very different impurity rejection in crystallization; a crystalline API and its amorphous state can have very different stability behavior. A thorough understanding of solid phases of a drug substance is crucial in the whole drug discovery and development life cycle.

Crystal pharmatech is at the cutting-edge of solid phase characterization, understanding and relevance to API and formulation processes. We provide high-quality and customer focused services in the following areas: solid state characterization, solid sate NMR service, preformulation studies, single crystal growth and structure determination, API form selection and optimization, crystallization development and optimization, manufacturing support, as well as being able to handle highly potent and cytotoxic compounds.