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Highlights of API Form and Solid-State Services

  • Serving over 800 clients worldwide

  • Supported solid form screening, crystallization, and preclinical formulation development of over 1,500 new drug molecules

  • The world’s leading technology supports the understanding of molecule and formulation with a high-end platform

  • High-quality service, a culture of confidentiality, and fast turnaround with cost-effective pricing

  • Customized solution for your molecule, spanning the entire drug lifecycle

Highlights of API Form and Solid-State Services

API Form and Solid-State Services

Solid Form Screening and Selection

Vetting of API solid forms for clinical studies is critical to maintain the integrity of downstream processes. Crystal Pharmatech makes best-in-class decisions utilizing a data-driven, multi-disciplinary approach based on institutional knowledge and comparative analysis.

Amorphous Solid Dispersions

Low water-soluble compounds can exhibit bio-performance issues such as poor PK exposure or non-linear PK exposure. To improve the bio-performance, amorphous solid dispersions of amorphous drug stabilized in polymer excipients are commonly developed for solubility enhancement.

Absolute Structure Determination

The physicochemical properties of a compound is closely related to its structure and often can be predicted from its structure. Single crystal X-ray data collection and structure elucidation is one of the best techniques to obtain the 3-dimentional structural information, including bond connectivity, chirality, solvate/water participation etc.

Crystallization Screening and Development

Crystallization is a critical unit operation in API manufacturing for both final product and intermediates. Desired product quality attributes can be obtained economically with high efficiency through well-designed and controlled crystallization processes.

Chiral Separation by Crystallization

More than 70% of drug candidates worldwide are chiral. Typically, for chiral API, only one enantiomer or diasteromer is biologically active or desirable. Therefore, the production of enantiopure compounds or diastereomers is imperative. In the production of small molecule drugs with desired chirality, separation via crystallization can be much more economical and environmentally favorable than chromatography.

Solid-State Characterization (FAST)

Our Solid State Characterization Service, which is referred to as Focused Analytical Solids Testing (FAST), covers many routine analyses encountered during pharmaceutical development. The FAST concept is directly aligned with our goal of partnering with organizations instead of merely providing data.

Solid-State NMR Analysis

Nuclear Magnetic Resonance (NMR) Spectroscopy is a ubiquitous analytical technique utilized across a wide range of disciplines.

Our Experience Becomes Your Competitive Advantages

Data Quality & Intellectual Protection
Project Management
  • Scientific Oriented

  • Flexibility

  • Effiency

Location
  • Labs in USA,Canada& China

  • Convenience and Flexbility

  • Cost Effective

Experience
  • Experienced Project Team

  • Scientific BD member

solid state physics research
Contact Us
Address:
Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey 08512, USA

Want to Know More?

If you have any questions, we will always be happy to help. Feel free to contact us by telephone, mail or leave a message.
Contact Us
bd_global@crystalpharmatech.com +1-609-604-8303
U.S
Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey 08512, USA
Canada
6800 Kitimat Rd, Unit 1, Mississauga, Ontario, Canada L5N 5M1
China
Suite B4-101, Biobay, 218 Xinghu Street, Suzhou Industrial Park, Suzhou, China, 215123
Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey 08512, USA
bd_global@crystalpharmatech.com +1-609-604-8303