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Oral Solid Dosage Forms

Most small molecule drugs achieve their therapeutic potential through Oral Solid Dosage (OSD) forms. At Crystal Pharmatech, we bridge the gap between complex molecular properties and high-performing drug products.

Our formulation team consists of technical experts who specialize in dosage form design and optimization. We don't believe in "one size fits all"—we design tailor-made formulations based on a deep-dive into your API’s material properties and your specific clinical goals.

OSD Capabilities

From standard tablets to complex multi-particulate systems, we develop robust dosage forms designed for stability and patient compliance.

Tablets
  • Immediate Release (IR)
  • Controlled Release (CR)
  • Bilayer Tablets
  • Mini-tablets
Capsules
  • Powder-filled capsules
  • Granule-in-capsule
  • Multi-particulates
  • Mini-tablets-in-capsule
Advanced Systems
  • Beads and Pellets
  • Functional Coating Systems

State-of-the-Art Processing

Utilizing top-tier equipment, our team delivers seamless formulation and process development across the manufacturing spectrum:

Granulation & Prep
  • Wet & Dry Granulation
  • Blending & Milling
  • Spray drying & Hot-melt extrusion (HME)
Final Dosage Form
  • Compression
  • Encapsulation
  • Film coating (pan or fluid bed)
Finishing
  • Bottle packaging
  • Blister packaging (Al-Al and Al-plastic)
  • Secondary packaging (labeling, carding, wallet, carton)
The Crystal Pharmatech Edge

Compaction Simulation, De-Risking Scale-Up

Scale up with confidence—not guesswork. Utilizing advanced tools like the STYL'One , compaction simulation is a core pillar of our technology. It allows us to characterize the properties of neat APIs, excipients, and blends with surgical precision.

Predict commercial-scale compression using grams of API
Simulate dwell time and compression force with mechanical modeling
Define roller compaction pressure
Define main compression pressure
Evaluate sticking risks
Evaluate over-lubrication risk
Evaluate bilayer tablet compression risk (e.g. delamination)
Reduce scale-up failures across different equipment
STYL'One Compaction Simulator
Compaction simulation raw data plot
Advanced Compaction Platform


By eliminating the "trial and error" of traditional scale-up, our compaction simulation becomes your most reliable tool for efficient, de-risked process design.

Achieve Your Success with Our Expertise

Have a question or need support with your project? Please complete the form, and our team will get back to you shortly.




Our capabilities span three specialized platforms:

  • Small Molecule

  • Crystal Bio Solutions

  • Crystal NAX


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Small Molecule Crystal Bio Solutions
Biologics Characterization and CMC Analytics Bioanalytical and Biomarker Services Quantitative Clinical Pharmacology (QCP)
Crystal NAX
DNA Synthesis RNA Synthesis LNP Formulation Services Analytical & Characterization Services Early-Phase Manufacturing Catalogue Products
Contact Us
bd_global@crystalpharmatech.com (925) 558-5040
U.S
NJ Sites: Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey, USA 08512

2005 Eastpark Blvd, Cranbury, New Jersey, USA 08512

CA Site: 7133 Koll Center Parkway, Suite 200, Pleasanton, California, USA 94566
Canada
6800 Kitimat Rd, Unit 1, Mississauga, Ontario, Canada L5N 5M1
China
No. 288, Jiangyun Road, Suzhou Industrial Park, Suzhou, China 215123

Floor 1, Bldg. 3, 68 Chunpu Road, Suzhou Industrial Park, Suzhou, China 215123
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NJ Sites: Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey, USA 08512

2005 Eastpark Blvd, Cranbury, New Jersey, USA 08512

CA Site: 7133 Koll Center Parkway, Suite 200, Pleasanton, California, USA 94566
bd_global@crystalpharmatech.com (925) 558-5040