The development of acceptable, palatable pediatric formulations is undergoing transformation within the industry today, driven by patient needs and regulatory requirements. Therefore, the demand for age-appropriate dosage form development will continue to increase with time. Mini-tablets, 2 mm in diameter, are an elegant way of delivering APIs to pediatric populations.
Better acceptability of dose size/volume
Tailored administration method
Ease and convenience of handling
Acceptable taste, color, mouth feel…
Wide range of doses in clinical study with a single formulation
Easy dose adjustment for different age groups
Possible to apply dose delivery modification (taste-masking, CR, etc.)
Amenable to various administration methods
Better stability thus longer shelf-life than liquid dosage
Single formulation for neonate to adolescent possible (minimum SKU, lower cost)
More accessible due to lower costs in manufacturing, shipping and storage
Our formulation team is experienced in mini-tablet technology with deep expertise in key unit operations such as compression, film coating and packaging. We have built the entire process train for minitablet formulation development from preliminary market formulation to final market formulation and to commercialization.