Chiral Separation by Crystallization

Economical & Environmentally Favorable Purification

More than 70% of drug candidates are chiral. Crystallization provides a more economical and sustainable alternative to traditional chromatography for producing enantiopure compounds.

Classical Resolution

Separating desired enantiomers via diastereomeric salt formation and crystallization.

Screening for optimal resolving agents
Identifying ideal polymorph & solvent systems
Full process design and optimization

Preferential Crystallization

Surpassing the 50% yield limit by combining active racemization with targeted crystallization.

Identification of proper racemizing agents
Advanced engineering to optimize enantiomer yield
Breaks the conventional 50% yield barrier

Systematic Advantage

Ternary Phase Diagrams

We do not rely on trial and error. Crystal Pharmatech utilizes Ternary Phase Diagrams as a powerful predictive tool to fundamentally understand system thermodynamics.

Immediate determination of purification feasibility
Direct guidance to optimal process conditions
Scientific precision in chiral drug purification

Predictive Thermodynamic Modeling

Achieve Your Success with Our Expertise

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Our capabilities span three specialized platforms:

Small Molecule
Crystal Bio Solutions
Crystal NAX

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