Mini-tablet

Precision Engineering for Pediatric Innovation

Pediatric patients are not simply "miniature adults." Arbitrarily breaking adult tablets leads to dosing inaccuracy and poor compliance. Our 2 mm mini-tablet platform provides a sophisticated, age-appropriate alternative.

At Crystal Pharmatech, our team provides comprehensive expertise in mini-tablet technology, from preliminary market formulation through to commercialization.

Strategic Advantages

Global Regulatory Alignment

We help clients navigate iPSP (FDA) and PIP (EMA) requirements for pediatric study plans.

High Acceptability

2 mm mini-tablets are proven to be as acceptable to infants as traditional syrups, without the stability issues of liquids.

Dosing Accuracy

Successfully achieved drug loads as low as 0.7% with exceptional content uniformity (7.5% RSD) for individual mini-tablet.

Technical Excellence in Mini-tablet Manufacturing

Developing mini-tablets requires balancing contradictory material properties and specialized engineering:

Challenge	Crystal Pharmatech Solution
Content Uniformity	Balancing the need for small particles (for uniformity) with large particles (for flowability) in the formulation.
Compression	Using specialized, custom-designed tooling and modified tablet presses to ensure high tablet strength and prevent breakage.
Film Coating	Managing prolonged spray times to prevent attrition during the coating process.
Packaging	Utilizing custom-designed equipment for accurate counting (vs. volume-based) for final presentation in capsules or stickpacks.