pKa/LogP/LogD Measurements

Earlier than ever before in the development timeline, biotech can achieve a comprehensive understanding of their molecule's physicochemical properties. Using material-sparing automation, Crystal Pharmatech guides its partners towards smarter decisions before more time and money is invested in their development process.

Automated and Accurate Measurements of pKa, Log P/D

A thorough understanding of the drug's pKa and Log P, determined through pH and UV metric titration methods, will:

• Guide a fundamental understanding of solid-state interactions and the overall crystalline form.

• Allow for more accurate prediction of physical, chemical, and biological in vivo predictions.

• Direct better formulation decisions and avoid costly mistakes when given solubility under different pH conditions.