First-Time-Right 3-STEP Approach

Developability Assessment

• Solid-State Characterization/FAST
• pKa/LogP/LogD Measurements
• Stability and Solubility Studies
• In-Silico PBPK Modeling and Simulation

API Form and Solid-State Research

• Solid Form Screening and Selection
• Single Crystal Growth & Structure Determination
• Solid-State NMR Analysis

Crystallization Development Services

• Crystallization Development
• Chiral Separation

Pre-formulation Studies

• Comprehensive Physicochemical Property Evaluation
• Excipient Selection and Compatibility Studies
• Formulations for PK/Efficacy/Tox Studies
• Animal Dosing Vehicle Selection
• Amorphous Solid Dispersions

Analytical Research and Quality Control

Formulation Development

• First-Time-Right Formulation Development
• Oral Solid Dosage Forms
• Amorphous Solid Dispersion (Spray Drying & Hot-melt Extrusion)
• Pediatric Formulation (Mini-tablet)

Clinical and Commercial GMP Manufacturing

• Clinical and Commercial Manufacturing

Clinical Supply

Solid-State, Crystallization & Preformulation

• Solid Form Screening
• Solid Form Developability Evaluation
• Absolute Structure Determination
• Crystallization Process Development

Formulation Development & Manufacturing

• Conventional Oral Solid Dosage Forms
• Bioavailability Enhancement for Insoluble Compounds & PROTAC & Oral Peptides
• Mini-tablet

Crystal Bio Solutions - Techniques & Capabilities Crystal NAX - Technology

Highlights News Events

Knowledge Hub

• Whitepaper
• Technical Insight
• Blog
• Case Study
• Presentation

Webinar Series

• Crystal Pharmatech Formulation Forum
• Mol2Med™ First-Time-Right Approach
• Selecting the Right API Form and Formulation
• Accelerating Drug Development through Collaboration