Blog - Crystal Pharmatech Co., Ltd.

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Blog

Short Half-Life vs. Once-a-Day Dosing: Breaking the Barrier

A short half-life doesn't rule out QD dosing. By leveraging Modified Release (MR) to flatten PK curves and addressing pillars like absorption windows and solubility, developers can bridge the gap from IR to once-daily regimens, ensuring patient compliance and therapeutic differentiation.

18 Mar 2026

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Blog

The Race to FIH: How Fast Can You Reach the Clinic?

We want to move fast to first-in-human. How quickly can formulation and clinical supply be ready for IND?In the high-stakes world of drug development, speed is the ultimate currency. But as the saying...

12 Mar 2026

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Blog

Peptide Crystallization Process Development: A Practical CMC Guide for Peptide APIs

Peptide crystallization process development can transform peptide API stability, filtration, and downstream manufacturability. Learn high-throughput screening, salt and polymorph screening, seeding, a...

11 Mar 2026

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Blog

Conquering the “Uncrystallizable”: Advanced Strategies for PROTAC Solid-Form Development

In the world of drug development, PROTACs (Proteolysis Targeting Chimeras) are notoriously difficult to crystallize. Their high molecular weight, inherent flexibility, and complex surface area often l...

10 Mar 2026

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Blog

The “Double-Limited” Challenge: Is ASD Always the Answer?

When a compound is both solubility and permeability limited, the reflex is often to reach for ASD. But is that always the right move? We walk through the systematic framework our team uses to find the true bottleneck.

05 Mar 2026

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