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Crystal Pharmatech | Reflecting on 2025
21 Feb 2026
Focus on PROTAC Compounds: Development Strategy
This series looks at the physicochemical challenges of PROTAC compounds. It explains how polymorph screening, salt/cocrystal optimization, and formulation and dosage-form development can improve solub...
Enhancing Drug Product Performance Through Spray Drying Parameter Optimization
As amorphous solid dispersions (ASDs) and their formulations advance from lab-scale research to clinical trials and, ultimately, to commercial production, manufacturing scales increase from grams to k...
Solid-State, Crystallization, and CMC Control for Drug Development – A Crystal Pharmatech Case Study Series
From early developability to late-stage specifications—polymorph/salt-cocrystal strategy, SCXRD/MicroED solutions, solvent & pathway design, drug-product form control, ASD crystalline-form limits...
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