Technical Articles
11 Apr 2025
Crystal’s Perspective: Polymorph Patent Landscape of 28 FDA-Approved Small Molecule Drugs in 2024
11 Apr 2025
Biologics are being used as drugs to treat a variety of human and animal diseases including autoimmune diseases such as rheumatoid arthritis. In the case of autoimmune diseases, some biologics interrupt signals, and pathways in the immune system to reduce the damage inflicted by the autoimmune conditions. Biologics can be very micro-heterogenous mixtures of structural variants that are difficult to identify and characterize. Biological products are generally heat sensitive and susceptible to microbial contamination.